Advanced Hyaluronans for Nutraceutical Use

Hyaluronic acid (HA), or its salt form sodium hyaluronate, is a widely used dietary supplement ingredient, known for its benefits in reducing wrinkles, improving skin properties, treating osteoarthritis, and supporting wound and mucosal healing.

ROELMI HPC has developed Full Spectrum HA Tech 2.0®, an advanced technology that goes beyond the conventional concept of hyaluronic acid, offering a more comprehensive and effective approach.

Innovation and efficacy walk hand-in-hand. ExceptionHYAL® is the proof of that

The Full Spectrum Technology, a finely modulated biofermentation process, provides the next-gen of hyaluronans able to deeply integrate into human biology of targeted tissues, matching skin, joints and mucosal needs, to deliver a concrete efficacy.

ROELMI HPC brings a renewed nutraceutical approach, with effective and safe higher-grade ingredients for selected applications.

Formulation is the science of “The whole is more than the sum of its parts”

The expertise of ROELMI HPC laboratories, and the versatility of ExceptionHYAL® hyaluronans, open the door to innovative ideas and sensory experiences to meet evolving trends and support Customers’ needs with stable and effective solutions.

FAQ

Hyaluronic acid (HA ) or sodium hyaluronate (SH) in its sodium salt form, is a naturally occurring polysaccharide in the human body. It plays a vital role in maintaining tissues hydration, viscosity, and joint lubrication. It also supports tissue regeneration, modulates inflammation, and protects against oxidative stress.

Sodium hyaluronate has different biological activities depending on its molecular weight:

  • High molecular weight has an anti-inflammatory and immunosuppressive activity, promoting tissue protection and homeostasis.
  • Medium and low molecular weight stimulates tissue regeneration, improves mucosal hydration and promotes keratinocyte proliferation, contributing to tissue renewal.

It is an advanced biofermentation process that produces sodium hyaluronate with a well-defined and complete range of molecular weights (from 20 to 3000 kDa). This mimics the body's natural profile, enabling more targeted and effective biological responses. The innovation? Overcoming the standard concept of molecular weight and focus on the biological efficacy and the needs of the target tissue.

Unlike traditional single molecular weight HAs, ExceptionHYAL® includes a full spectrum of molecular sizes that work synergistically, providing both immediate benefits (hydration, protection) and long-term effects (regeneration, stimulation of endogenous HA production).

ExceptionHYAL® line is designed to integrate fully into the physiology of different tissues:

  • ExceptionHYAL® Star: targeting skin beauty and anti-aging from within
  • ExceptionHYAL® Jump: designed for joint pain reduction and enhanced mobility
  • ExceptionHYAL® Relief: created to effectively alleviate unpleasant digestive issues as heartburn and acid reflux
  • ExceptionHYAL® Blossom: realized to alleviate the symptoms of vaginal atrophy (urinary urgency, itching, burning, irritation, dryness involving significant pain during sex) thanks to a moisturizing and recovery effect.
  • ExceptionHYAL® Wink: developed to support ocular well-being and improve vision comfort.

Yes. Thanks to controlled biofermentation (not animal-derived), ExceptionHYAL® products ensure high purity, safety, and no allergenic risk, making them suitable even for sensitive individuals.
The efficacy is always assured by clinical trials on human volunteers. Ask us for scientific publications at info@roelmihpc.com.

ROELMI HPC is a leading company in the innovation of active and functional ingredients for Health & Personal Care, driven by science and sustainability. It specializes in cutting-edge biotechnologies and circular economy principles. The company partners with brands worldwide to create effective, safe, and eco-designed products. If you're interested, contact us at info@roelmihpc.com

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